LTP Assay From 4 Mouse Hippocampal Slices

Perform LTP assay on 4 samples simultaneously.
High-quality evoked signals without interference from stimulus artifacts.
Easy-to-find the best stimulus electrode to elicit LTP.
Ideal solution for evaluation of drug effects on LTP.

Application Note:

Higher throughput micro-electrode array to investigate of role of NMDA receptor in synaptic plasticity in acute brain slices

Platform for LTP assay from 4 hippocampal slices.

System Configuration

(1) MED64 Main Amplifier (MED-A64MD1)
(1) MED64 Head Amplifier (MED-A64HE1S)
(4) MED Mini Connector (MED-C04)
(4) MED Probe16 (MED-PG515A)
(1) Mobius Software
(1) Acquisition PC
(4) Perfusion Cap With Tubes
(2) MED ThermoBase(MED-CPB01)
(2) ThermoClamp™-1 Controller
(2) Peristaltic Pump (4channels)

Data obtained from a LTP assay. Left shows hippocampal slices obtained from 1 mouse brain. Middle panel shows evoked EPSP traces before (blue trace) and after (red trace) theta burst stimulation. The right panel shows data obtained from each slice.